The aspartyl protease BACE1 cleaves neuregulin 1 and is involved in myelination and is a candidate drug target for Alzheimer's disease, where it acts as the I2-secretase cleaving the amyloid precursor protein .
http://www.citeulike.org/user/cdsouthan/article/12225117
http://www.citeulike.org/user/cdsouthan/article/12225117
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