People who have a buildup of certain proteins in the brain and spinal fluid have an increased likelihood of developing Alzheimer's disease, but it's currently unclear who will develop these protein accumulations.
http://www.eurekalert.org/pub_releases/2013-04/cp-ngm032813.php
http://www.eurekalert.org/pub_releases/2013-04/cp-ngm032813.php
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